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Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination
Chronic demyelination is a pathological hallmark of multiple sclerosis (MS). Only a minority of MS lesions remyelinates completely. Enhancing remyelination is, therefore, a major aim of future MS therapies. Here we took a novel approach to identify factors that may inhibit or support endogenous remy...
Autores principales: | Mohan, Hema, Friese, Anita, Albrecht, Stefanie, Krumbholz, Markus, Elliott, Christina L, Arthur, Ariel, Menon, Ramesh, Farina, Cinthia, Junker, Andreas, Stadelmann, Christine, Barnett, Susan C, Huitinga, Inge, Wekerle, Hartmut, Hohlfeld, Reinhard, Lassmann, Hans, Kuhlmann, Tanja, Linington, Chris, Meinl, Edgar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359505/ https://www.ncbi.nlm.nih.gov/pubmed/25589163 http://dx.doi.org/10.1186/s40478-014-0168-9 |
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