Int6 reduction activates stromal fibroblasts to enhance transforming activity in breast epithelial cells

BACKGROUND: The INT6 gene was first discovered as a site of integration in mouse mammary tumors by the mouse mammary tumor virus; however, INT6’s role in the development of human breast cancer remains largely unknown. By gene silencing, we have previously shown that repressing INT6 promotes transfor...

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Detalles Bibliográficos
Autores principales: Suo, Jinfeng, Medina, Daniel, Herrera, Sabrina, Zheng, Ze-Yi, Jin, Lei, Chamness, Gary C, Contreras, Alejandro, Gutierrez, Carolina, Hilsenbeck, Susan, Umar, Arzu, Foekens, John A, Hanash, Samir, Schiff, Rachel, Zhang, Xiang H-F, Chang, Eric C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359526/
https://www.ncbi.nlm.nih.gov/pubmed/25774287
http://dx.doi.org/10.1186/s13578-015-0001-6

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