Cargando…

Pharmacological characterisation of murine α4β1δ GABA(A) receptors expressed in Xenopus oocytes

BACKGROUND: GABA(A) receptor subunit composition has a profound effect on the receptor’s physiological and pharmacological properties. The receptor β subunit is widely recognised for its importance in receptor assembly, trafficking and post-translational modifications, but its influence on extrasyna...

Descripción completa

Detalles Bibliográficos
Autores principales:	Villumsen, Inge S, Wellendorph, Petrine, Smart, Trevor G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359537/ https://www.ncbi.nlm.nih.gov/pubmed/25887256 http://dx.doi.org/10.1186/s12868-015-0148-4

Ejemplares similares

Impact of ε and θ subunits on pharmacological properties of α3β1 GABA(A )receptors expressed in Xenopus oocytes
por: Ranna, Martin, et al.
Publicado: (2006)

Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects
por: Lie, Maria E. K., et al.
Publicado: (2020)

CaMKIIα as a Promising Drug Target for Ischemic Grey Matter
por: Griem-Krey, Nane, et al.
Publicado: (2022)

Resveratrol Inhibits GABA(C) ρ Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes
por: Lee, Byung-Hwan, et al.
Publicado: (2013)

Low Expression in Xenopus Oocytes and Unusual Functional Properties of α(1)β(2)γ(2) GABA(A) Receptors with Non-Conventional Subunit Arrangement
por: Baur, Roland, et al.
Publicado: (2017)

The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform
por: Khumpirapang, Nattakanwadee, et al.
Publicado: (2022)

Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABA(A) receptors
por: Falk-Petersen, Christina Birkedahl, et al.
Publicado: (2020)

Stoichiometry of δ subunit containing GABA(A) receptors
por: Patel, B, et al.
Publicado: (2014)

Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1
por: Kickinger, Stefanie, et al.
Publicado: (2021)

Cell surface expression of murine, rat, and human Fc receptors by Xenopus oocytes
Publicado: (1984)

Xenopus Oocytes: A Tool to Decipher Molecular Specificity of Insecticides towards Mammalian and Insect GABA—A Receptors
por: Bertaud, Anaïs, et al.
Publicado: (2022)

Actin in Xenopus oocytes
Publicado: (1978)

Snake neurotoxin α-bungarotoxin is an antagonist at native GABA(A) receptors
por: Hannan, Saad, et al.
Publicado: (2015)

Gat1 (Gaba:Na(+):Cl(−)) Cotransport Function: Kinetic Studies in Giant Xenopus Oocyte Membrane Patches
por: Lu, Chin-Chih, et al.
Publicado: (1999)

Microinjection of Xenopus Laevis Oocytes
por: Cohen, Sarah, et al.
Publicado: (2009)

Pharmacological and Biophysical Characteristics of Picrotoxin-Resistant, δSubunit-Containing GABA(A) Receptors
por: Shu, Hong-Jin, et al.
Publicado: (2021)

Assembly of Torpedo acetylcholine receptors in Xenopus oocytes
Publicado: (1991)

Steady-state activation of the high-affinity isoform of the α4β2δ GABA(A) receptor
por: Pierce, Spencer R., et al.
Publicado: (2019)

Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels
por: Cristofori-Armstrong, Ben, et al.
Publicado: (2015)

GABA Potency at GABA(A) Receptors Found in Synaptic and Extrasynaptic Zones
por: Mortensen, Martin, et al.
Publicado: (2012)

Gat1 (Gaba:Na(+):Cl(−)) Cotransport Function: Steady State Studies in Giant Xenopus Oocyte Membrane Patches
por: Lu, Chin-Chih, et al.
Publicado: (1999)

The “www” of Xenopus laevis Oocytes: The Why, When, What of Xenopus laevis Oocytes in Membrane Transporters Research
por: Bhatt, Manan, et al.
Publicado: (2022)

THE EFFECTS OF VINBLASTINE ON ISOLATED XENOPUS OOCYTES
por: Dumont, James N., et al.
Publicado: (1972)

Visualizing RNA Localization in Xenopus Oocytes
por: Gagnon, James A., et al.
Publicado: (2010)

In Vitro Reconstruction of Xenopus Oocyte Ovulation
por: Tokmakov, Alexander A., et al.
Publicado: (2019)

I–J loop involvement in the pharmacological profile of CLC-K channels expressed in Xenopus oocytes
por: Gradogna, Antonella, et al.
Publicado: (2014)

Agonist-dependent Single Channel Current and Gating in α(4)β(2)δ and α(1)β(2)γ(2S) GABA(A) Receptors
por: Keramidas, Angelo, et al.
Publicado: (2008)

Xenopus laevis lectin is localized at several sites in Xenopus oocytes, eggs, and embryos
Publicado: (1983)

Exploring the molecular determinants for subtype-selectivity of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate-inhibitors
por: Kickinger, Stefanie, et al.
Publicado: (2020)

Expression of epithelial Na channels in Xenopus oocytes
Publicado: (1990)

Translational control by cytoplasmic polyadenylation in Xenopus oocytes
por: Radford, Helois E., et al.
Publicado: (2008)

Mechanism for the selection of nuclear polypeptides in Xenopus oocytes
Publicado: (1978)

Hyperpolarization-activated chloride currents in Xenopus oocytes
Publicado: (1994)

Regulation of ALF Promoter Activity in Xenopus Oocytes
por: Li, Dan, et al.
Publicado: (2009)

Optimizing plant transporter expression in Xenopus oocytes
por: Feng, Huimin, et al.
Publicado: (2013)

Orthogonality of Pyrrolysine tRNA in the Xenopus oocyte
por: Infield, Daniel T., et al.
Publicado: (2018)

The Xenopus Oocyte: A Tool for Membrane Biology
por: Limon, Agenor, et al.
Publicado: (2023)

Electrogenic Sulfate/Chloride Exchange in Xenopus Oocytes Mediated by Murine AE1 E699Q
por: Chernova, M.N., et al.
Publicado: (1997)

Human α3β4 Neuronal Nicotinic Receptors Show Different Stoichiometry if They Are Expressed in Xenopus Oocytes or Mammalian HEK293 Cells
por: Krashia, Paraskevi, et al.
Publicado: (2010)

Synthesis and Pharmacological Evaluation of [(11)C]4-Methoxy-N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the δ-Subunit-Containing γ-Aminobutyric Acid Type A Receptors
por: L’Estrade, Elina T., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_tq8mci7k189ikbtefn8gsphj30