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Inhibition of TGF-β by a novel PPAR-γ agonist, chrysin, salvages β-receptor stimulated myocardial injury in rats through MAPKs-dependent mechanism
BACKGROUND: Pharmacological stimulation of peroxisome proliferator-activated receptor-gamma (PPAR-γ) has been recognized as a molecular switch in alleviating myocardial injury through modulating oxidative, inflammatory and apoptotic signaling pathways. This study was designed to elucidate the effect...
Autores principales: | Rani, Neha, Bharti, Saurabh, Bhatia, Jagriti, Tomar, Ameesha, Nag, T C, Ray, Ruma, Arya, Dharamvir Singh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359541/ https://www.ncbi.nlm.nih.gov/pubmed/25774203 http://dx.doi.org/10.1186/s12986-015-0004-7 |
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