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Concise Reviews: Assisted Reproductive Technologies to Prevent Transmission of Mitochondrial DNA Disease

While the fertilized egg inherits its nuclear DNA from both parents, the mitochondrial DNA is strictly maternally inherited. Cells contain multiple copies of mtDNA, each of which encodes 37 genes, which are essential for energy production by oxidative phosphorylation. Mutations can be present in all...

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Detalles Bibliográficos
Autores principales:	Richardson, Jessica, Irving, Laura, Hyslop, Louise A, Choudhary, Meenakshi, Murdoch, Alison, Turnbull, Douglass M, Herbert, Mary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Translational and Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359624/ https://www.ncbi.nlm.nih.gov/pubmed/25377180 http://dx.doi.org/10.1002/stem.1887

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