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Distinct regulation of Maf1 for lifespan extension by Protein kinase A and Sch9

The Protein kinase A (PKA) and Sch9 regulates cell growth as well as lifespan in Saccharomyces cerevisiae. Maf1 is a RNA polymerase III (Pol III) inhibitor that tailors 5S rRNA and tRNA production in response to various environmental cues. Both PKA and Sch9 have been shown to phosphorylate Maf1 in v...

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Detalles Bibliográficos
Autores principales: Cai, Ying, Wei, Yue-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359695/
https://www.ncbi.nlm.nih.gov/pubmed/25720796