Sertraline-Related Bleeding Tendency: Could It Be Dose-Dependent?

Selective serotonin reuptake inhibitors (SSRIs) are reported to be associated with increased bleeding tendency. While findings of recent studies explain a lot about the pathophysiology of this side-effect, there is a general tendency to discontinue SSRIs as harmful medications. We report two instanc...

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Autores principales: Eslami Shahrbabki, Mahin, Eslami Shahrbabaki, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mazandaran University of Medical Sciences 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359729/
https://www.ncbi.nlm.nih.gov/pubmed/25780379
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author Eslami Shahrbabki, Mahin
Eslami Shahrbabaki, Amir
author_facet Eslami Shahrbabki, Mahin
Eslami Shahrbabaki, Amir
author_sort Eslami Shahrbabki, Mahin
collection PubMed
description Selective serotonin reuptake inhibitors (SSRIs) are reported to be associated with increased bleeding tendency. While findings of recent studies explain a lot about the pathophysiology of this side-effect, there is a general tendency to discontinue SSRIs as harmful medications. We report two instances of dose-dependent relations between sertraline and bleeding tendency. Bleeding diathesis was alleviated by adjusting dosage of medication. It could be argued that benefits of SSRIs could outweigh this potential and probably avoidable side-effect; if dose-adjustment is properly implemented.
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spelling pubmed-43597292015-03-16 Sertraline-Related Bleeding Tendency: Could It Be Dose-Dependent? Eslami Shahrbabki, Mahin Eslami Shahrbabaki, Amir Iran J Psychiatry Behav Sci Case Report Selective serotonin reuptake inhibitors (SSRIs) are reported to be associated with increased bleeding tendency. While findings of recent studies explain a lot about the pathophysiology of this side-effect, there is a general tendency to discontinue SSRIs as harmful medications. We report two instances of dose-dependent relations between sertraline and bleeding tendency. Bleeding diathesis was alleviated by adjusting dosage of medication. It could be argued that benefits of SSRIs could outweigh this potential and probably avoidable side-effect; if dose-adjustment is properly implemented. Mazandaran University of Medical Sciences 2014 /pmc/articles/PMC4359729/ /pubmed/25780379 Text en © 2014, Iranian Journal of Psychiatry and Behavioral Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Eslami Shahrbabki, Mahin
Eslami Shahrbabaki, Amir
Sertraline-Related Bleeding Tendency: Could It Be Dose-Dependent?
title Sertraline-Related Bleeding Tendency: Could It Be Dose-Dependent?
title_full Sertraline-Related Bleeding Tendency: Could It Be Dose-Dependent?
title_fullStr Sertraline-Related Bleeding Tendency: Could It Be Dose-Dependent?
title_full_unstemmed Sertraline-Related Bleeding Tendency: Could It Be Dose-Dependent?
title_short Sertraline-Related Bleeding Tendency: Could It Be Dose-Dependent?
title_sort sertraline-related bleeding tendency: could it be dose-dependent?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359729/
https://www.ncbi.nlm.nih.gov/pubmed/25780379
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