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Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes
Varp (VPS9-ankyrin repeat protein) was originally identified as an activator of small GTPase Rab21 through its VPS9 domain, but it has subsequently been shown to function as a Rab32/38 effector through its first ANKR1 domain. Although these functions of Varp are important for melanogenesis, Varp con...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359733/ https://www.ncbi.nlm.nih.gov/pubmed/25661869 http://dx.doi.org/10.1242/bio.201411114 |