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Heterodimeric TALENs induce targeted heritable mutations in the crustacean Daphnia magna
Transcription activator-like effector nucleases (TALENs) are artificial nucleases harboring a customizable DNA-binding domain and a FokI nuclease domain. The high specificity of the DNA-binding domain and the ease of design have enabled researchers to use TALENs for targeted mutagenesis in various o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359742/ https://www.ncbi.nlm.nih.gov/pubmed/25681393 http://dx.doi.org/10.1242/bio.20149738 |