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Heterodimeric TALENs induce targeted heritable mutations in the crustacean Daphnia magna

Transcription activator-like effector nucleases (TALENs) are artificial nucleases harboring a customizable DNA-binding domain and a FokI nuclease domain. The high specificity of the DNA-binding domain and the ease of design have enabled researchers to use TALENs for targeted mutagenesis in various o...

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Detalles Bibliográficos
Autores principales: Naitou, Akiko, Kato, Yasuhiko, Nakanishi, Takashi, Matsuura, Tomoaki, Watanabe, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359742/
https://www.ncbi.nlm.nih.gov/pubmed/25681393
http://dx.doi.org/10.1242/bio.20149738