Cargando…

The CRISPR/Cas9 system inactivates latent HIV-1 proviral DNA

BACKGROUND: Highly active antiretroviral therapy (HAART) has transformed HIV-1 infection from a deadly disease to a manageable chronic illness, albeit does not provide a cure. The recently developed genome editing system called CRISPR/Cas9 offers a new tool to inactivate the integrated latent HIV-1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Weijun, Lei, Rongyue, Le Duff, Yann, Li, Jian, Guo, Fei, Wainberg, Mark A, Liang, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359768/ https://www.ncbi.nlm.nih.gov/pubmed/25808449 http://dx.doi.org/10.1186/s12977-015-0150-z

Ejemplares similares

Inactivation of Latent HIV-1 Proviral DNA Using Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 Treatment and the Assessment of Off-Target Effects
por: Xu, Yufan, et al.
Publicado: (2021)

CRISPR-Cas9 Dual-gRNA Attack Causes Mutation, Excision and Inversion of the HIV-1 Proviral DNA
por: Binda, Caroline S., et al.
Publicado: (2020)

CRISPR/Cas9 Ablation of Integrated HIV-1 Accumulates Proviral DNA Circles with Reformed Long Terminal Repeats
por: Lai, Michele, et al.
Publicado: (2021)

Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
por: Ebina, Hirotaka, et al.
Publicado: (2013)

CRISPR/Cas9 Genome Editing to Disable the Latent HIV-1 Provirus
por: Panfil, Amanda R., et al.
Publicado: (2018)

Elimination of infectious HIV DNA by CRISPR–Cas9
por: Das, Atze T, et al.
Publicado: (2019)

CRISPR/Cas9: a double-edged sword when used to combat HIV infection
por: Liang, Chen, et al.
Publicado: (2016)

Heterochromatin delays CRISPR-Cas9 mutagenesis but does not influence the outcome of mutagenic DNA repair
por: Kallimasioti-Pazi, Eirini M., et al.
Publicado: (2018)

Minimal genome-wide human CRISPR-Cas9 library
por: Gonçalves, Emanuel, et al.
Publicado: (2021)

Potent and Targeted Activation of Latent HIV-1 Using the CRISPR/dCas9 Activator Complex
por: Saayman, Sheena M, et al.
Publicado: (2016)

T cell-specific inactivation of mouse CD2 by CRISPR/Cas9
por: Beil-Wagner, Jane, et al.
Publicado: (2016)

WU-CRISPR: characteristics of functional guide RNAs for the CRISPR/Cas9 system
por: Wong, Nathan, et al.
Publicado: (2015)

In Vitro Pre-validation of Gene Editing by CRISPR/Cas9 Ribonucleoprotein
por: Mehravar, Maryam, et al.
Publicado: (2019)

Damaging the Integrated HIV Proviral DNA with TALENs
por: Strong, Christy L., et al.
Publicado: (2015)

HIV-1 tropism: a comparison between RNA and proviral DNA in routine clinical samples from Chilean patients
por: Ferrer, Pablo, et al.
Publicado: (2013)

Efficient Breeding of Early-Maturing Rice Cultivar by Editing PHYC via CRISPR/Cas9
por: Li, Bin, et al.
Publicado: (2021)

CRISPR/Cas9-mediated target validation of the splicing inhibitor Pladienolide B
por: Aouida, Mustapha, et al.
Publicado: (2016)

Improving the genome editing efficiency of CRISPR/Cas9 in Arabidopsis and Medicago truncatula
por: Wolabu, Tezera W., et al.
Publicado: (2020)

Genetic modification of the protozoan Eimeria tenella using the CRISPR/Cas9 system
por: Tang, Xinming, et al.
Publicado: (2020)

What did CRISPR-Cas9 accomplish in its first 10 years?
por: Khlidj, Yehya
Publicado: (2023)

Gene Inactivation by CRISPR-Cas9 in Nicotiana tabacum BY-2 Suspension Cells
por: Mercx, Sébastien, et al.
Publicado: (2016)

A small cassette enables conditional gene inactivation by CRISPR/Cas9
por: Guzzardo, Paloma M., et al.
Publicado: (2017)

The Advance of CRISPR-Cas9-Based and NIR/CRISPR-Cas9-Based Imaging System
por: Qiao, Huanhuan, et al.
Publicado: (2021)

CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections
por: van Diemen, Ferdy R., et al.
Publicado: (2016)

Live imaging and tracking of genome regions in CRISPR/dCas9 knock-in mice
por: Duan, Jinzhi, et al.
Publicado: (2018)

Modulating CRISPR gene drive activity through nucleocytoplasmic localization of Cas9 in S. cerevisiae
por: Goeckel, Megan E., et al.
Publicado: (2019)

Assessing the efficacy of CRISPR/Cas9 genome editing in the wheat pathogen Parastagonspora nodorum
por: Khan, Haseena, et al.
Publicado: (2020)

An improved method for precise genome editing in zebrafish using CRISPR-Cas9 technique
por: Gasanov, Eugene V., et al.
Publicado: (2021)

A high-efficient and naked-eye visible CRISPR/Cas9 system in Arabidopsis
por: Kong, Wenwen, et al.
Publicado: (2023)

Disabling Cas9 by an anti-CRISPR DNA mimic
por: Shin, Jiyung, et al.
Publicado: (2017)

Highly efficient gene inactivation by adenoviral CRISPR/Cas9 in human primary cells
por: Voets, Olaf, et al.
Publicado: (2017)

Acute gene inactivation in the adult mouse liver using the CRISPR-Cas9 technology
por: Wang, Xiao, et al.
Publicado: (2021)

Programming PAM antennae for efficient CRISPR-Cas9 DNA editing
por: Wang, Fei, et al.
Publicado: (2020)

Global detection of DNA repair outcomes induced by CRISPR–Cas9
por: Liu, Mengzhu, et al.
Publicado: (2021)

CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting
por: Courtney, D G, et al.
Publicado: (2016)

CRISPR-Cas13a Inhibits HIV-1 Infection
por: Yin, Lijuan, et al.
Publicado: (2020)

CRISPR based editing of SIV proviral DNA in ART treated non-human primates
por: Mancuso, Pietro, et al.
Publicado: (2020)

A redesigned CRISPR/Cas9 system for marker-free genome editing in Plasmodium falciparum
por: Lu, Junnan, et al.
Publicado: (2016)

Development of an Efficient Genome Editing Method by CRISPR/Cas9 in a Fish Cell Line
por: Dehler, Carola E., et al.
Publicado: (2016)

Efficient and specific generation of knockout mice using Campylobacter jejuni CRISPR/Cas9 system
por: Lee, Jae Young, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_40u5vt51u64kn2o6fs3goqcqil