Alpha-enolase promotes cell glycolysis, growth, migration, and invasion in non-small cell lung cancer through FAK-mediated PI3K/AKT pathway

BACKGROUND: During tumor formation and expansion, increasing glucose metabolism is necessary for unrestricted growth of tumor cells. Expression of key glycolytic enzyme alpha-enolase (ENO1) is controversial and its modulatory mechanisms are still unclear in non-small cell lung cancer (NSCLC). METHOD...

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Detalles Bibliográficos
Autores principales: Fu, Qiao-Fen, Liu, Yan, Fan, Yue, Hua, Sheng-Ni, Qu, Hong-Ying, Dong, Su-Wei, Li, Rui-Lei, Zhao, Meng-Yang, Zhen, Yan, Yu, Xiao-Li, Chen, Yi-Yu, Luo, Rong-Cheng, Li, Rong, Li, Li-Bo, Deng, Xiao-Jie, Fang, Wei-Yi, Liu, Zhen, Song, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359783/
https://www.ncbi.nlm.nih.gov/pubmed/25887760
http://dx.doi.org/10.1186/s13045-015-0117-5

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