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Sequencing the CHO DXB11 genome reveals regional variations in genomic stability and haploidy
BACKGROUND: The DHFR negative CHO DXB11 cell line (also known as DUX-B11 and DUKX) was historically the first CHO cell line to be used for large scale production of heterologous proteins and is still used for production of a number of complex proteins. RESULTS: Here we present the genomic sequence o...
Autores principales: | Kaas, Christian Schrøder, Kristensen, Claus, Betenbaugh, Michael J, Andersen, Mikael Rørdam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359788/ https://www.ncbi.nlm.nih.gov/pubmed/25887056 http://dx.doi.org/10.1186/s12864-015-1391-x |
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