Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner

Statins are widely used in the treatment of hypercholesterolemia and their side effects on muscles are well established. Conversely, data are sparse regarding the safety of this class of drugs in subjects who engage in sports, particularly those who have intense sports activity. We report the case o...

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Autores principales: Toussirot, Éric, Michel, Fabrice, Meneveau, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359831/
https://www.ncbi.nlm.nih.gov/pubmed/25815236
http://dx.doi.org/10.1155/2015/721078
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author Toussirot, Éric
Michel, Fabrice
Meneveau, Nicolas
author_facet Toussirot, Éric
Michel, Fabrice
Meneveau, Nicolas
author_sort Toussirot, Éric
collection PubMed
description Statins are widely used in the treatment of hypercholesterolemia and their side effects on muscles are well established. Conversely, data are sparse regarding the safety of this class of drugs in subjects who engage in sports, particularly those who have intense sports activity. We report the case of a marathon runner who presented with acute rhabdomyolysis during competition while being under rosuvastatin treatment. This case raises the question of the need for temporary discontinuation of statin therapy when intense physical activity is planned.
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spelling pubmed-43598312015-03-26 Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner Toussirot, Éric Michel, Fabrice Meneveau, Nicolas Case Rep Rheumatol Case Report Statins are widely used in the treatment of hypercholesterolemia and their side effects on muscles are well established. Conversely, data are sparse regarding the safety of this class of drugs in subjects who engage in sports, particularly those who have intense sports activity. We report the case of a marathon runner who presented with acute rhabdomyolysis during competition while being under rosuvastatin treatment. This case raises the question of the need for temporary discontinuation of statin therapy when intense physical activity is planned. Hindawi Publishing Corporation 2015 2015-02-28 /pmc/articles/PMC4359831/ /pubmed/25815236 http://dx.doi.org/10.1155/2015/721078 Text en Copyright © 2015 Éric Toussirot et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Toussirot, Éric
Michel, Fabrice
Meneveau, Nicolas
Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner
title Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner
title_full Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner
title_fullStr Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner
title_full_unstemmed Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner
title_short Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner
title_sort rhabdomyolysis occurring under statins after intense physical activity in a marathon runner
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359831/
https://www.ncbi.nlm.nih.gov/pubmed/25815236
http://dx.doi.org/10.1155/2015/721078
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