BRCA Genetic Screening in Middle Eastern and North African: Mutational Spectrum and Founder BRCA1 Mutation (c.798_799delTT) in North African

Background. The contribution of BRCA1 mutations to both hereditary and sporadic breast and ovarian cancer (HBOC) has not yet been thoroughly investigated in MENA. Methods. To establish the knowledge about BRCA1 mutations and their correlation with the clinical aspect in diagnosed cases of HBOC in ME...

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Detalles Bibliográficos
Autores principales: Laraqui, Abdelilah, Uhrhammer, Nancy, EL Rhaffouli, Hicham, Sekhsokh, Yassine, Lahlou-Amine, Idriss, Bajjou, Tahar, Hilali, Farida, El Baghdadi, Jamila, Al Bouzidi, Abderrahmane, Bakri, Youssef, Amzazi, Said, Bignon, Yves-Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359853/
https://www.ncbi.nlm.nih.gov/pubmed/25814778
http://dx.doi.org/10.1155/2015/194293

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