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Lack of Association between JAK3 Gene Polymorphisms and Cardiovascular Disease in Spanish Patients with Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased cardiovascular (CV) mortality. JAK/STAT signalling pathway is involved in autoimmune diseases and in the atherosclerotic process. JAK3 is a highly promising target for immunomodulatory drugs an...

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Detalles Bibliográficos
Autores principales: García-Bermúdez, Mercedes, López-Mejías, Raquel, Genre, Fernanda, Castañeda, Santos, Corrales, Alfonso, Llorca, Javier, González-Juanatey, Carlos, Ubilla, Begoña, Miranda-Filloy, José A., Pina, Trinitario, Gómez-Vaquero, Carmen, Rodríguez-Rodríguez, Luis, Fernández-Gutiérrez, Benjamín, Balsa, Alejandro, Pascual-Salcedo, Dora, López-Longo, Francisco J., Carreira, Patricia, Blanco, Ricardo, Martín, Javier, González-Gay, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359874/
https://www.ncbi.nlm.nih.gov/pubmed/25815310
http://dx.doi.org/10.1155/2015/318364