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Lack of Association between JAK3 Gene Polymorphisms and Cardiovascular Disease in Spanish Patients with Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased cardiovascular (CV) mortality. JAK/STAT signalling pathway is involved in autoimmune diseases and in the atherosclerotic process. JAK3 is a highly promising target for immunomodulatory drugs an...
Autores principales: | García-Bermúdez, Mercedes, López-Mejías, Raquel, Genre, Fernanda, Castañeda, Santos, Corrales, Alfonso, Llorca, Javier, González-Juanatey, Carlos, Ubilla, Begoña, Miranda-Filloy, José A., Pina, Trinitario, Gómez-Vaquero, Carmen, Rodríguez-Rodríguez, Luis, Fernández-Gutiérrez, Benjamín, Balsa, Alejandro, Pascual-Salcedo, Dora, López-Longo, Francisco J., Carreira, Patricia, Blanco, Ricardo, Martín, Javier, González-Gay, Miguel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359874/ https://www.ncbi.nlm.nih.gov/pubmed/25815310 http://dx.doi.org/10.1155/2015/318364 |
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