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The ACE2/Apelin Signaling, MicroRNAs, and Hypertension

The renin-angiotensin aldosterone system (RAAS) plays a pivotal role in the development of hypertension. Angiotensin converting enzyme 2 (ACE2), which primarily metabolises angiotensin (Ang) II to generate the beneficial heptapeptide Ang-(1-7), serves as a negative regulator of the RAAS. Apelin is a...

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Detalles Bibliográficos
Autores principales: Chen, Lai-Jiang, Xu, Ran, Yu, Hui-Min, Chang, Qing, Zhong, Jiu-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359877/
https://www.ncbi.nlm.nih.gov/pubmed/25815211
http://dx.doi.org/10.1155/2015/896861