Extracellular vesicles, tissue factor, cancer and thrombosis – discussion themes of the ISEV 2014 Educational Day

Although the association between cancer and venous thromboembolism (VTE) has long been known, the mechanisms are poorly understood. Circulating tissue factor–bearing extracellular vesicles have been proposed as a possible explanation for the increased risk of VTE observed in some types of cancer. Th...

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Detalles Bibliográficos
Autores principales: Gardiner, Chris, Harrison, Paul, Belting, Mattias, Böing, Anita, Campello, Elena, Carter, Bob S., Collier, Mary E., Coumans, Frank, Ettelaie, Camille, van Es, Nick, Hochberg, Fred H., Mackman, Nigel, Rennert, Robert C., Thaler, Johannes, Rak, Janusz, Nieuwland, Rienk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359985/
https://www.ncbi.nlm.nih.gov/pubmed/25773446
http://dx.doi.org/10.3402/jev.v4.26901
Descripción
Sumario:Although the association between cancer and venous thromboembolism (VTE) has long been known, the mechanisms are poorly understood. Circulating tissue factor–bearing extracellular vesicles have been proposed as a possible explanation for the increased risk of VTE observed in some types of cancer. The International Society for Extracellular Vesicles (ISEV) and International Society on Thrombosis and Haemostasis (ISTH) held a joint Educational Day in April 2014 to discuss the latest developments in this field. This review discusses the themes of that event and the ISEV 2014 meeting that followed.

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