CFH Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye

PURPOSE: Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in people 50 years of age or older in developed countries. The homozygous CC genotype in the complement factor H (CFH) Y402H single nucleotide polymorphism (SNP; rs1061170) is widely recognized as a risk f...

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Detalles Bibliográficos
Autores principales: Wang, Jay Ching Chieh, Cao, Sijia, Wang, Aikun, To, Eleanor, Law, Geoffrey, Gao, Jiangyuan, Zhang, Dean, Cui, Jing Z., Matsubara, Joanne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360164/
https://www.ncbi.nlm.nih.gov/pubmed/25814824

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