Agonist and Antagonist Effects of Aripiprazole on D(2)-Like Receptors Controlling Rat Brain Dopamine Synthesis Depend on the Dopaminergic Tone

BACKGROUND: The atypical antipsychotic drug aripiprazole binds with high affinity to a number of G protein coupled receptors, including dopamine D(2) receptors, where its degree of efficacy as a partial agonist remains controversial. METHODS: We examined the properties of aripiprazole at D(2)-like a...

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Detalles Bibliográficos
Autores principales: Ma, Guo Fen, Raivio, Noora, Sabrià, Josefa, Ortiz, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360222/
https://www.ncbi.nlm.nih.gov/pubmed/25522390
http://dx.doi.org/10.1093/ijnp/pyu046

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