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Paliperidone Prevents Brain Toll-Like Receptor 4 Pathway Activation and Neuroinflammation in Rat Models of Acute and Chronic Restraint Stress

BACKGROUND: Alterations in the innate immune/inflammatory system have been proposed to underlie the pathophysiology of psychotic disease, but the mechanisms implicated remain elusive. The main agents of the innate immunity are the family of toll-like receptors (TLRs), which detect circulating pathog...

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Detalles Bibliográficos
Autores principales: MacDowell, KS, Caso, JR, Martín-Hernández, D, Madrigal, JL, Leza, JC, García-Bueno, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360250/
https://www.ncbi.nlm.nih.gov/pubmed/25522409
http://dx.doi.org/10.1093/ijnp/pyu070