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Synthesis and Biological Evaluation of Indolyl-Pyridinyl-Propenones Having Either Methuosis or Microtubule Disruption Activity

[Image: see text] Methuosis is a form of nonapoptotic cell death characterized by an accumulation of macropinosome-derived vacuoles with eventual loss of membrane integrity. Small molecules inducing methuosis could offer significant advantages compared to more traditional anticancer drug therapies t...

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Detalles Bibliográficos
Autores principales:	Trabbic, Christopher J., Overmeyer, Jean H., Alexander, Evan M., Crissman, Emily J., Kvale, Heather M., Smith, Marcie A., Erhardt, Paul W., Maltese, William A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360382/ https://www.ncbi.nlm.nih.gov/pubmed/25654321 http://dx.doi.org/10.1021/jm501997q

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