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The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA

The HIV Rev protein routes viral RNAs containing the Rev Response Element (RRE) through the Crm1 nuclear export pathway to the cytoplasm where viral proteins are expressed and genomic RNA is delivered to assembling virions. The RRE assembles a Rev oligomer that displays nuclear export sequences (NES...

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Detalles Bibliográficos
Autores principales:	Booth, David S, Cheng, Yifan, Frankel, Alan D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360530/ https://www.ncbi.nlm.nih.gov/pubmed/25486595 http://dx.doi.org/10.7554/eLife.04121

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