Cargando…
Target Mediated Drug Disposition Model of CPHPC in Patients with Systemic Amyloidosis
The amyloid deposits that cause disease in systemic amyloidosis always contain the normal plasma protein, serum amyloid P (SAP) component. SAP is the target of a novel immunotherapy approach now being developed to eliminate amyloid deposits. The treatment is enabled by, and critically depends on, th...
Autores principales: | Sahota, T, Berges, A, Barton, S, Cookson, L, Zamuner, S, Richards, D |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360666/ https://www.ncbi.nlm.nih.gov/pubmed/26225229 http://dx.doi.org/10.1002/psp4.15 |
Ejemplares similares
-
Interaction of serum amyloid P component with hexanoyl bis(d-proline) (CPHPC)
por: Kolstoe, Simon E., et al.
Publicado: (2014) -
A Tutorial on Target-Mediated Drug Disposition (TMDD) Models
por: Dua, P, et al.
Publicado: (2015) -
Reduced and optimized trial designs for drugs described by a target mediated drug disposition model
por: Brekkan, A., et al.
Publicado: (2018) -
Dynamics of target-mediated drug disposition: characteristic profiles and parameter identification
por: Peletier, Lambertus A., et al.
Publicado: (2012) -
Target‐Mediated Drug Disposition Model for Bispecific Antibodies: Properties, Approximation, and Optimal Dosing Strategy
por: Schropp, Johannes, et al.
Publicado: (2019)