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Preclinical development and first-in-human study of ATX-MS-1467 for immunotherapy of MS

OBJECTIVE: The study was designed to test the efficacy of ATX-MS-1467 in a relevant preclinical model and to assess its safety for the treatment of patients with secondary progressive multiple sclerosis (SPMS). METHODS: ATX-MS-1467 was tested for its ability to suppress experimental autoimmune encep...

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Detalles Bibliográficos
Autores principales: Streeter, Heather B., Rigden, Rachel, Martin, Keith F., Scolding, Neil J., Wraith, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360798/
https://www.ncbi.nlm.nih.gov/pubmed/25798453
http://dx.doi.org/10.1212/NXI.0000000000000093