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A chromatin activity based chemoproteomic approach reveals a transcriptional repressome for gene-specific silencing

Immune cells develop endotoxin tolerance (ET) after prolonged stimulation. ET increases the level of a repression mark H3K9me2 in the transcriptional-silent chromatin specifically associated with pro-inflammatory genes. However, it is not clear what proteins are functionally involved in this process...

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Detalles Bibliográficos
Autores principales:	Liu, Cui, Yu, Yanbao, Liu, Feng, Wei, Xin, Wrobel, John A., Gunawardena, Harsha P., Zhou, Li, Jin, Jian, Chen, Xian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360912/ https://www.ncbi.nlm.nih.gov/pubmed/25502336 http://dx.doi.org/10.1038/ncomms6733

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