Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic

Oligodendrocyte death contributes to the pathogenesis of the inflammatory demyelinating disease multiple sclerosis (MS). Nevertheless, current MS therapies are mainly immunomodulatory and have demonstrated limited ability to inhibit MS progression. Protection of oligodendrocytes is therefore a desir...

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Detalles Bibliográficos
Autores principales: Way, Sharon W., Podojil, Joseph R., Clayton, Benjamin L., Zaremba, Anita, Collins, Tassie L., Kunjamma, Rejani B., Robinson, Andrew P., Brugarolas, Pedro, Miller, Robert H., Miller, Stephen D., Popko, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360920/
https://www.ncbi.nlm.nih.gov/pubmed/25766071
http://dx.doi.org/10.1038/ncomms7532

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