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Prion Protein and Copper Cooperatively Protect Neurons by Modulating NMDA Receptor Through S-nitrosylation

Aims: Several neurodegenerative disorders show alterations in glutamatergic synapses and increased susceptibility to excitotoxicity. Mounting evidence suggests a central role for the cellular prion protein (PrP(C)) in neuroprotection. Therefore, the loss of PrP(C) function occurring in prion disorde...

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Detalles Bibliográficos
Autores principales:	Gasperini, Lisa, Meneghetti, Elisa, Pastore, Beatrice, Benetti, Federico, Legname, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc. 2015
Materias:	Original Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361008/ https://www.ncbi.nlm.nih.gov/pubmed/25490055 http://dx.doi.org/10.1089/ars.2014.6032

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