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Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function
Translation initiation in the hepatitis C virus (HCV) occurs through a cap-independent mechanism that involves an internal ribosome entry site (IRES) capable of interacting with and utilizing the eukaryotic translational machinery. In this review, we focus on the structural configuration of the diff...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361049/ https://www.ncbi.nlm.nih.gov/pubmed/25352252 http://dx.doi.org/10.1002/wrna.1268 |