Cargando…
Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function
Translation initiation in the hepatitis C virus (HCV) occurs through a cap-independent mechanism that involves an internal ribosome entry site (IRES) capable of interacting with and utilizing the eukaryotic translational machinery. In this review, we focus on the structural configuration of the diff...
Autores principales: | Khawaja, Anas, Vopalensky, Vaclav, Pospisek, Martin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361049/ https://www.ncbi.nlm.nih.gov/pubmed/25352252 http://dx.doi.org/10.1002/wrna.1268 |
Ejemplares similares
-
IRESite—a tool for the examination of viral and cellular internal ribosome entry sites
por: Mokrejš, Martin, et al.
Publicado: (2010) -
HCVIVdb: The hepatitis-C IRES variation database
por: Floden, Evan W., et al.
Publicado: (2016) -
Characterization of Hepatitis C Virus IRES Quasispecies – From the Individual to the Pool
por: Vopálenský, Václav, et al.
Publicado: (2018) -
Giardiavirus Internal Ribosome Entry Site Has an Apparently Unique Mechanism of Initiating Translation
por: Garlapati, Srinivas, et al.
Publicado: (2009) -
N-Terminal Domain of Nuclear IL-1α Shows Structural Similarity to the C-Terminal Domain of Snf1 and Binds to the HAT/Core Module of the SAGA Complex
por: Zamostna, Blanka, et al.
Publicado: (2012)