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Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function

Translation initiation in the hepatitis C virus (HCV) occurs through a cap-independent mechanism that involves an internal ribosome entry site (IRES) capable of interacting with and utilizing the eukaryotic translational machinery. In this review, we focus on the structural configuration of the diff...

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Detalles Bibliográficos
Autores principales: Khawaja, Anas, Vopalensky, Vaclav, Pospisek, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361049/
https://www.ncbi.nlm.nih.gov/pubmed/25352252
http://dx.doi.org/10.1002/wrna.1268

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