Colorectal Adenomas Contain Multiple Somatic Mutations That Do Not Coincide with Synchronous Adenocarcinoma Specimens

We have performed a comparative ultrasequencing study of multiple colorectal lesions obtained simultaneously from four patients. Our data show that benign lesions (adenomatous or hyperplastic polyps) contain a high mutational load. Additionally multiple synchronous colorectal lesions show non overla...

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Detalles Bibliográficos
Autores principales: Vaqué, José P., Martínez, Nerea, Varela, Ignacio, Fernández, Fidel, Mayorga, Marta, Derdak, Sophia, Beltrán, Sergi, Moreno, Thaidy, Almaraz, Carmen, De las Heras, Gonzalo, Bayés, Mónica, Gut, Ivo, Crespo, Javier, Piris, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361059/
https://www.ncbi.nlm.nih.gov/pubmed/25775023
http://dx.doi.org/10.1371/journal.pone.0119946

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