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Prevalence and predictors of germline CDKN2A mutations for melanoma cases from Australia, Spain and the United Kingdom

BACKGROUND: Mutations in the CDKN2A and CDK4 genes predispose to melanoma. From three case-control studies of cutaneous melanoma, we estimated the prevalence and predictors of these mutations for people from regions with widely differing latitudes and melanoma incidence. METHODS: Population-based ca...

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Detalles Bibliográficos
Autores principales: Harland, Mark, Cust, Anne E, Badenas, Celia, Chang, Yu-Mei, Holland, Elizabeth A, Aguilera, Paula, Aitken, Joanne F, Armstrong, Bruce K, Barrett, Jennifer H, Carrera, Cristina, Chan, May, Gascoyne, Joanne, Giles, Graham G, Agha-Hamilton, Chantelle, Hopper, John L, Jenkins, Mark A, Kanetsky, Peter A, Kefford, Richard F, Kolm, Isabel, Lowery, Johanna, Malvehy, Josep, Ogbah, Zighereda, Puig-Butille, Joan-Anton, Orihuela-Segalés, Jordi, Randerson-Moor, Juliette A, Schmid, Helen, Taylor, Claire F, Whitaker, Linda, Bishop, D Timothy, Mann, Graham J, Newton-Bishop, Julia A, Puig, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361137/
https://www.ncbi.nlm.nih.gov/pubmed/25780468
http://dx.doi.org/10.1186/1897-4287-12-20