Cyclosporin A Disrupts Notch Signaling and Vascular Lumen Maintenance

Cyclosporin A (CSA) suppresses immune function by blocking the cyclophilin A and calcineurin/NFAT signaling pathways. In addition to immunosuppression, CSA has also been shown to have a wide range of effects in the cardiovascular system including disruption of heart valve development, smooth muscle...

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Detalles Bibliográficos
Autores principales: Pandey, Raghav, Botros, Mark A., Nacev, Benjamin A., Albig, Allan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361394/
https://www.ncbi.nlm.nih.gov/pubmed/25775018
http://dx.doi.org/10.1371/journal.pone.0119279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361394/
https://www.ncbi.nlm.nih.gov/pubmed/25775018
http://dx.doi.org/10.1371/journal.pone.0119279

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