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Down-Regulation of Deacetylase HDAC6 Inhibits the Melanoma Cell Line A375.S2 Growth through ROS-Dependent Mitochondrial Pathway

Previous studies have shown that histone deacetylase 6 (HDAC6) plays critical roles in many cellular processes related to cancer. However, its biological roles in the development of melanoma remain unexplored. Our aim was to investigate whether HDAC6 has a biological role in human melanoma developme...

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Detalles Bibliográficos
Autores principales: Bai, Jun, Lei, Yun, An, Gai-li, He, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361412/
https://www.ncbi.nlm.nih.gov/pubmed/25774669
http://dx.doi.org/10.1371/journal.pone.0121247

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