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Phosphatidylinositol 3-Kinase γ Is Required for the Development of Experimental Cerebral Malaria

Experimental cerebral malaria (ECM) is characterized by a strong immune response, with leukocyte recruitment, blood-brain barrier breakdown and hemorrhage in the central nervous system. Phosphatidylinositol 3-kinase γ (PI3Kγ) is central in signaling diverse cellular functions. Using PI3Kγ-deficient...

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Detalles Bibliográficos
Autores principales:	Lacerda-Queiroz, Norinne, Brant, Fatima, Rodrigues, David Henrique, Vago, Juliana Priscila, Rachid, Milene Alvarenga, Sousa, Lirlândia Pires, Teixeira, Mauro Martins, Teixeira, Antonio Lucio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361544/ https://www.ncbi.nlm.nih.gov/pubmed/25775137 http://dx.doi.org/10.1371/journal.pone.0119633

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