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Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel Activity

Magnesium (Mg(2+)) is essential for enzymatic activity, brain function and muscle contraction. Blood Mg(2+) concentrations are tightly regulated between 0.7 and 1.1 mM by Mg(2+) (re)absorption in kidney and intestine. The apical entry of Mg(2+) in (re)absorbing epithelial cells is mediated by the tr...

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Detalles Bibliográficos
Autores principales: Blanchard, Maxime G., de Baaij, Jeroen H. F., Verkaart, Sjoerd A. J., Lameris, Anke L., Basmadjian, Christine, Zhao, Qian, Désaubry, Laurent, Bindels, René J. M., Hoenderop, Joost G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361557/
https://www.ncbi.nlm.nih.gov/pubmed/25774985
http://dx.doi.org/10.1371/journal.pone.0119028

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