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Concentrated Protein Body Product Derived from Rice Endosperm as an Oral Tolerogen for Allergen-Specific Immunotherapy—A New Mucosal Vaccine Formulation against Japanese Cedar Pollen Allergy
The endoplasmic reticulum-derived type-I protein body (PB-I) from rice endosperm cells is an ideal candidate formulation for the oral delivery of bioencapsulated peptides as tolerogens for allergen-specific immunotherapy. In the present study, PBs containing the deconstructed Japanese cedar pollen a...
Autores principales: | Wakasa, Yuhya, Takagi, Hidenori, Watanabe, Nobumasa, Kitamura, Noriko, Fujiwara, Yoshihiro, Ogo, Yuko, Hayashi, Shimpei, Yang, Lijun, Ohta, Masaru, Thet Tin, Wai Wai, Sekikawa, Kenji, Takano, Makoto, Ozawa, Kenjirou, Hiroi, Takachika, Takaiwa, Fumio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361645/ https://www.ncbi.nlm.nih.gov/pubmed/25774686 http://dx.doi.org/10.1371/journal.pone.0120209 |
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