Cargando…
Effects of Iron Overload on the Bone Marrow Microenvironment in Mice
OBJECTIVE: Using a mouse model, Iron Overload (IO) induced bone marrow microenvironment injury was investigated, focusing on the involvement of reactive oxygen species (ROS). METHODS: Mice were intraperitoneally injected with iron dextran (12.5, 25, or 50mg) every three days for two, four, and six w...
Autores principales: | Zhang, Yuchen, Zhai, Wenjing, Zhao, Mingfeng, Li, Deguan, Chai, Xiao, Cao, Xiaoli, Meng, Juanxia, Chen, Jie, Xiao, Xia, Li, Qing, Mu, Juan, Shen, Jichun, Meng, Aimin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361683/ https://www.ncbi.nlm.nih.gov/pubmed/25774923 http://dx.doi.org/10.1371/journal.pone.0120219 |
Ejemplares similares
-
ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice
por: Chai, Xiao, et al.
Publicado: (2015) -
Corrigendum: ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice
por: Chai, Xiao, et al.
Publicado: (2017) -
Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice
por: Jin, Xin, et al.
Publicado: (2018) -
Inhibition of iron overload-induced apoptosis and necrosis of bone marrow mesenchymal stem cells by melatonin
por: Yang, Fan, et al.
Publicado: (2017) -
Protective effects of deferasirox and N-acetyl-L-cysteine on iron overload-injured bone marrow
por: Shen, J.C., et al.
Publicado: (2017)