Paradoxical Effects of All-Trans-Retinoic Acid on Lupus-Like Disease in the MRL/lpr Mouse Model

Roles of all-trans-retinoic acid (tRA), a metabolite of vitamin A (VA), in both tolerogenic and immunogenic responses are documented. However, how tRA affects the development of systemic autoimmunity is poorly understood. Here we demonstrate that tRA have paradoxical effects on the development of au...

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Detalles Bibliográficos
Autores principales: Liao, Xiaofeng, Ren, Jingjing, Wei, Cheng-Hsin, Ross, A. Catharine, Cecere, Thomas E., Jortner, Bernard S., Ahmed, S. Ansar, Luo, Xin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361690/
https://www.ncbi.nlm.nih.gov/pubmed/25775135
http://dx.doi.org/10.1371/journal.pone.0118176

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