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Alcohol calculations and their uncertainty

A dilution model is widely used to link blood alcohol concentration and the quantity of alcohol consumed. Whilst some authors use the total body water formulation of that model, others use the Widmark Factor formulation. A paper by Forrest gave a table of example values of the Widmark Factor and Bar...

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Autor principal: Searle, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361698/
https://www.ncbi.nlm.nih.gov/pubmed/24644224
http://dx.doi.org/10.1177/0025802414524385
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author Searle, John
author_facet Searle, John
author_sort Searle, John
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description A dilution model is widely used to link blood alcohol concentration and the quantity of alcohol consumed. Whilst some authors use the total body water formulation of that model, others use the Widmark Factor formulation. A paper by Forrest gave a table of example values of the Widmark Factor and Barbour, based on Forrest’s work and using Forrest’s computer program, subsequently presented Forrest’s results by way of a chart. Whilst the results of Forrest and Barbour are often used interchangeably, there is a significant difference between them on the factors for women. This paper examines the source of the unexpected discrepancy. It is essential to quote an error range, in blood alcohol concentration calculations, for the results. The extent of that error range was investigated by Gullberg who also employed the Widmark Factor formulation. Gullberg concluded that when reporting a calculated blood alcohol concentration, a coefficient of variation of ±21% should be applied. Similarly, Gullberg concluded that when calculating the volume of drink, a coefficient of variation of 12½% should be applied. The present paper derives and publishes the formulae for calculating this coefficient of variation. It is then shown that Gullberg’s conclusions are mistaken: the coefficient of variation is not some fixed percentage but must be calculated in each case.
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spelling pubmed-43616982015-04-10 Alcohol calculations and their uncertainty Searle, John Med Sci Law Technical Report A dilution model is widely used to link blood alcohol concentration and the quantity of alcohol consumed. Whilst some authors use the total body water formulation of that model, others use the Widmark Factor formulation. A paper by Forrest gave a table of example values of the Widmark Factor and Barbour, based on Forrest’s work and using Forrest’s computer program, subsequently presented Forrest’s results by way of a chart. Whilst the results of Forrest and Barbour are often used interchangeably, there is a significant difference between them on the factors for women. This paper examines the source of the unexpected discrepancy. It is essential to quote an error range, in blood alcohol concentration calculations, for the results. The extent of that error range was investigated by Gullberg who also employed the Widmark Factor formulation. Gullberg concluded that when reporting a calculated blood alcohol concentration, a coefficient of variation of ±21% should be applied. Similarly, Gullberg concluded that when calculating the volume of drink, a coefficient of variation of 12½% should be applied. The present paper derives and publishes the formulae for calculating this coefficient of variation. It is then shown that Gullberg’s conclusions are mistaken: the coefficient of variation is not some fixed percentage but must be calculated in each case. SAGE Publications 2015-01 /pmc/articles/PMC4361698/ /pubmed/24644224 http://dx.doi.org/10.1177/0025802414524385 Text en © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(http://www.uk.sagepub.com/aboutus/openaccess.htm).
spellingShingle Technical Report
Searle, John
Alcohol calculations and their uncertainty
title Alcohol calculations and their uncertainty
title_full Alcohol calculations and their uncertainty
title_fullStr Alcohol calculations and their uncertainty
title_full_unstemmed Alcohol calculations and their uncertainty
title_short Alcohol calculations and their uncertainty
title_sort alcohol calculations and their uncertainty
topic Technical Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361698/
https://www.ncbi.nlm.nih.gov/pubmed/24644224
http://dx.doi.org/10.1177/0025802414524385
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