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H-Ras Mediates the Inhibitory Effect of Epidermal Growth Factor on the Epithelial Na(+) Channel
The present study investigates the role of small G-proteins of the Ras family in the epidermal growth factor (EGF)-activated cellular signalling pathway that downregulates activity of the epithelial Na(+) channel (ENaC). We found that H-Ras is a key component of this EGF-activated cellular signallin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361710/ https://www.ncbi.nlm.nih.gov/pubmed/25774517 http://dx.doi.org/10.1371/journal.pone.0116938 |