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H-Ras Mediates the Inhibitory Effect of Epidermal Growth Factor on the Epithelial Na(+) Channel

The present study investigates the role of small G-proteins of the Ras family in the epidermal growth factor (EGF)-activated cellular signalling pathway that downregulates activity of the epithelial Na(+) channel (ENaC). We found that H-Ras is a key component of this EGF-activated cellular signallin...

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Detalles Bibliográficos
Autores principales:	Lee, Il-Ha, Song, Sung-Hee, Cook, David I., Dinudom, Anuwat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361710/ https://www.ncbi.nlm.nih.gov/pubmed/25774517 http://dx.doi.org/10.1371/journal.pone.0116938

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