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Increased fragmentation of sleep-wake cycles in the 5XFAD mouse model of Alzheimer’s disease
Sleep perturbations including fragmented sleep with frequent night-time awakenings and daytime naps are common in patients with Alzheimer’s disease (AD), and these daily disruptions are a major factor for institutionalization. The objective of this study was to investigate if sleep-wake patterns are...
Autores principales: | Sethi, Mansi, Joshi, Shreyas S., Webb, Robin L., Beckett, Tina L., Donohue, Kevin D., Murphy, M. Paul, O’Hara, Bruce F, Duncan, Marilyn J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361816/ https://www.ncbi.nlm.nih.gov/pubmed/25637807 http://dx.doi.org/10.1016/j.neuroscience.2015.01.035 |
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