The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids

Receptor tyrosine kinases (RTKs) play a critical role in diverse cellular processes and their activity is regulated by lipids in the surrounding membrane, including PIP(2) (phosphatidylinositol-4,5-bisphosphate) in the inner leaflet, and GM3 (monosialodihexosylganglioside) in the outer leaflet. Howe...

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Detalles Bibliográficos
Autores principales: Hedger, George, Sansom, Mark S. P., Koldsø, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361843/
https://www.ncbi.nlm.nih.gov/pubmed/25779975
http://dx.doi.org/10.1038/srep09198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361843/
https://www.ncbi.nlm.nih.gov/pubmed/25779975
http://dx.doi.org/10.1038/srep09198

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