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The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids
Receptor tyrosine kinases (RTKs) play a critical role in diverse cellular processes and their activity is regulated by lipids in the surrounding membrane, including PIP(2) (phosphatidylinositol-4,5-bisphosphate) in the inner leaflet, and GM3 (monosialodihexosylganglioside) in the outer leaflet. Howe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361843/ https://www.ncbi.nlm.nih.gov/pubmed/25779975 http://dx.doi.org/10.1038/srep09198 |