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Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view

Considering the many secondary natural metabolites available from plants, phenolic compounds play a particularly important role in human health as they occur in significant amounts in many fruits, vegetables and medicinal plants. In this review natural phenolic compounds of plant origin with signifi...

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Detalles Bibliográficos
Autores principales: Sun, Qiu, Heilmann, Jörg, König, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361970/
https://www.ncbi.nlm.nih.gov/pubmed/25815077
http://dx.doi.org/10.3762/bjoc.11.28
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author Sun, Qiu
Heilmann, Jörg
König, Burkhard
author_facet Sun, Qiu
Heilmann, Jörg
König, Burkhard
author_sort Sun, Qiu
collection PubMed
description Considering the many secondary natural metabolites available from plants, phenolic compounds play a particularly important role in human health as they occur in significant amounts in many fruits, vegetables and medicinal plants. In this review natural phenolic compounds of plant origin with significant anti-angiogenic properties are discussed. Thirteen representatives from eight different natural or natural-like phenolic subclasses are presented with an emphasis on their synthesis and methods to modify the parent compounds. When available, the consequence of structural variation on the pharmacological activity of the molecules is described.
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spelling pubmed-43619702015-03-26 Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view Sun, Qiu Heilmann, Jörg König, Burkhard Beilstein J Org Chem Review Considering the many secondary natural metabolites available from plants, phenolic compounds play a particularly important role in human health as they occur in significant amounts in many fruits, vegetables and medicinal plants. In this review natural phenolic compounds of plant origin with significant anti-angiogenic properties are discussed. Thirteen representatives from eight different natural or natural-like phenolic subclasses are presented with an emphasis on their synthesis and methods to modify the parent compounds. When available, the consequence of structural variation on the pharmacological activity of the molecules is described. Beilstein-Institut 2015-02-16 /pmc/articles/PMC4361970/ /pubmed/25815077 http://dx.doi.org/10.3762/bjoc.11.28 Text en Copyright © 2015, Sun et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Review
Sun, Qiu
Heilmann, Jörg
König, Burkhard
Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view
title Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view
title_full Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view
title_fullStr Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view
title_full_unstemmed Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view
title_short Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view
title_sort natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361970/
https://www.ncbi.nlm.nih.gov/pubmed/25815077
http://dx.doi.org/10.3762/bjoc.11.28
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