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Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view
Considering the many secondary natural metabolites available from plants, phenolic compounds play a particularly important role in human health as they occur in significant amounts in many fruits, vegetables and medicinal plants. In this review natural phenolic compounds of plant origin with signifi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361970/ https://www.ncbi.nlm.nih.gov/pubmed/25815077 http://dx.doi.org/10.3762/bjoc.11.28 |
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author | Sun, Qiu Heilmann, Jörg König, Burkhard |
author_facet | Sun, Qiu Heilmann, Jörg König, Burkhard |
author_sort | Sun, Qiu |
collection | PubMed |
description | Considering the many secondary natural metabolites available from plants, phenolic compounds play a particularly important role in human health as they occur in significant amounts in many fruits, vegetables and medicinal plants. In this review natural phenolic compounds of plant origin with significant anti-angiogenic properties are discussed. Thirteen representatives from eight different natural or natural-like phenolic subclasses are presented with an emphasis on their synthesis and methods to modify the parent compounds. When available, the consequence of structural variation on the pharmacological activity of the molecules is described. |
format | Online Article Text |
id | pubmed-4361970 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Beilstein-Institut |
record_format | MEDLINE/PubMed |
spelling | pubmed-43619702015-03-26 Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view Sun, Qiu Heilmann, Jörg König, Burkhard Beilstein J Org Chem Review Considering the many secondary natural metabolites available from plants, phenolic compounds play a particularly important role in human health as they occur in significant amounts in many fruits, vegetables and medicinal plants. In this review natural phenolic compounds of plant origin with significant anti-angiogenic properties are discussed. Thirteen representatives from eight different natural or natural-like phenolic subclasses are presented with an emphasis on their synthesis and methods to modify the parent compounds. When available, the consequence of structural variation on the pharmacological activity of the molecules is described. Beilstein-Institut 2015-02-16 /pmc/articles/PMC4361970/ /pubmed/25815077 http://dx.doi.org/10.3762/bjoc.11.28 Text en Copyright © 2015, Sun et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
spellingShingle | Review Sun, Qiu Heilmann, Jörg König, Burkhard Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view |
title | Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view |
title_full | Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view |
title_fullStr | Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view |
title_full_unstemmed | Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view |
title_short | Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view |
title_sort | natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361970/ https://www.ncbi.nlm.nih.gov/pubmed/25815077 http://dx.doi.org/10.3762/bjoc.11.28 |
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