Copper-catalyzed cascade reactions of α,β-unsaturated esters with keto esters

A copper-catalyzed cascade reaction of α,β-unsaturated esters with keto esters is reported. It features a copper-catalyzed reductive aldolization followed by a lactonization. This method provides a facile approach to prepare γ-carboxymethyl-γ-lactones and δ-carboxymethyl-δ-lactones under mild reacti...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zhengning, Wang, Chongnian, Li, Zengchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362015/
https://www.ncbi.nlm.nih.gov/pubmed/25815072
http://dx.doi.org/10.3762/bjoc.11.23
_version_ 1782361741085114368
author Li, Zhengning
Wang, Chongnian
Li, Zengchang
author_facet Li, Zhengning
Wang, Chongnian
Li, Zengchang
author_sort Li, Zhengning
collection PubMed
description A copper-catalyzed cascade reaction of α,β-unsaturated esters with keto esters is reported. It features a copper-catalyzed reductive aldolization followed by a lactonization. This method provides a facile approach to prepare γ-carboxymethyl-γ-lactones and δ-carboxymethyl-δ-lactones under mild reaction conditions.
format Online
Article
Text
id pubmed-4362015
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-43620152015-03-26 Copper-catalyzed cascade reactions of α,β-unsaturated esters with keto esters Li, Zhengning Wang, Chongnian Li, Zengchang Beilstein J Org Chem Full Research Paper A copper-catalyzed cascade reaction of α,β-unsaturated esters with keto esters is reported. It features a copper-catalyzed reductive aldolization followed by a lactonization. This method provides a facile approach to prepare γ-carboxymethyl-γ-lactones and δ-carboxymethyl-δ-lactones under mild reaction conditions. Beilstein-Institut 2015-02-06 /pmc/articles/PMC4362015/ /pubmed/25815072 http://dx.doi.org/10.3762/bjoc.11.23 Text en Copyright © 2015, Li et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Li, Zhengning
Wang, Chongnian
Li, Zengchang
Copper-catalyzed cascade reactions of α,β-unsaturated esters with keto esters
title Copper-catalyzed cascade reactions of α,β-unsaturated esters with keto esters
title_full Copper-catalyzed cascade reactions of α,β-unsaturated esters with keto esters
title_fullStr Copper-catalyzed cascade reactions of α,β-unsaturated esters with keto esters
title_full_unstemmed Copper-catalyzed cascade reactions of α,β-unsaturated esters with keto esters
title_short Copper-catalyzed cascade reactions of α,β-unsaturated esters with keto esters
title_sort copper-catalyzed cascade reactions of α,β-unsaturated esters with keto esters
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362015/
https://www.ncbi.nlm.nih.gov/pubmed/25815072
http://dx.doi.org/10.3762/bjoc.11.23
work_keys_str_mv AT lizhengning coppercatalyzedcascadereactionsofabunsaturatedesterswithketoesters
AT wangchongnian coppercatalyzedcascadereactionsofabunsaturatedesterswithketoesters
AT lizengchang coppercatalyzedcascadereactionsofabunsaturatedesterswithketoesters

Ejemplares similares