2-(1-Hydroxypropyn-2-yl)-1-vinylpyrroles: the first successful Favorsky ethynylation of pyrrolecarbaldehydes

1-Vinylpyrrole-2-carbaldehydes react with acetylene at atmospheric pressure in a NaOH/EtOH/DMSO system at 7–10 °C to afford 2-(1-hydroxypropyn-2-yl)-1-vinylpyrroles in 53–94% yield. Thus, the first base-mediated direct ethynylation of pyrrolecarbaldehydes with free acetylene under modified condition...

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Detalles Bibliográficos
Autores principales: Ivanov, A V, Shcherbakova, V S, Ushakov, I A, Sobenina, L N, Petrova, O V, Mikhaleva, A I, Trofimov, B A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362022/
https://www.ncbi.nlm.nih.gov/pubmed/25815074
http://dx.doi.org/10.3762/bjoc.11.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362022/
https://www.ncbi.nlm.nih.gov/pubmed/25815074
http://dx.doi.org/10.3762/bjoc.11.25

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