Allogeneic lymphocyte-licensed DCs expand T cells with improved antitumor activity and resistance to oxidative stress and immunosuppressive factors

Adoptive T-cell therapy of cancer is a treatment strategy where T cells are isolated, activated, in some cases engineered, and expanded ex vivo before being reinfused to the patient. The most commonly used T-cell expansion methods are either anti-CD3/CD28 antibody beads or the “rapid expansion proto...

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Detalles Bibliográficos
Autores principales: Jin, Chuan, Yu, Di, Hillerdal, Victoria, Wallgren, AnnaCarin, Karlsson-Parra, Alex, Essand, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362340/
https://www.ncbi.nlm.nih.gov/pubmed/26015949
http://dx.doi.org/10.1038/mtm.2014.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362340/
https://www.ncbi.nlm.nih.gov/pubmed/26015949
http://dx.doi.org/10.1038/mtm.2014.1

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