Different protein composition and functional properties of adeno-associated virus-6 vector manufactured from the culture medium and cell lysates

Vectors based on recombinant adeno-associated viruses (rAAV) attract a growing interest for human gene therapy. Recently, it was shown that many rAAV serotypes produced by transient transfection of human embryonic kidney 293 cell line (HEK293) are efficiently released into culture medium and functio...

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Detalles Bibliográficos
Autores principales: Denard, Jerome, Jenny, Christine, Blouin, Véronique, Moullier, Philippe, Svinartchouk, Fedor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362353/
https://www.ncbi.nlm.nih.gov/pubmed/26015972
http://dx.doi.org/10.1038/mtm.2014.31

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